Please, help in a Blood Cancer case of a 19 year old girl!-Please read the first post

[Vezunchik]

Kimdur Rossiyada yashavotganlarga asosan.
bundan 3 kun oldin vest.ru eshitgandim. shu bir hafta ichida Moskvada Qon Raki masalalari bo`yicha konferentsiya bo`lib o`tibdi. Unda Rano Holmatova (yoki shu nomga o`hshash) degan bir ayol chiqib bu fond shu kasalga chalinganlarni davolash masalalarini izlashayatgani va fondlar, bolnitsalar bilan ishlashayotganini aytgandi. Bu ayol shu kabi fondni rahbari ekan.

Lekin 2 kundan beri Internetda hali topa olganim yo`q bu fondni.
Nobodi kimdur eshitgan bo`lsa surishtirib ko`ringlar balkim ular bilar qaysi Fondlar moliyaviy yordam bera olishini.

[Royal]

http://www.parthen-impact.com/cgi-bin/pco/6_05EHA/public/index.cgi?unit=pub_search_results&form_id=303&abstract_id=37&fsession=yes

http://www.parthen-impact.com/cgi-bin/pco/6_05EHA/public/index.cgi?unit=pub_search_results&form_id=303&abstract_id=32&fsession=yes

http://www.parthen-impact.com/cgi-bin/pco/6_05EHA/public/index.cgi?unit=pub_search_results&form_id=303&abstract_id=55&fsession=yes

THE EFFICIENCY OF NEW HEMOCORRECTOR IN COMPLEX TREATMENT OF IRON DEFICIENCY ANEMIA

Author: K.K. Bakirkhanova, Institute of Hematology and Transfusion, Tashkent, Uzbekistan
Co-author(s): N.M. Holmatova, Institute of Hematology, Tashkent, Uzbekistan
M.K. Bakirhanov, Institute of Hematology, Tashkent, Uzbekistan

Topic: 6A. Anemia / Red blood cells
Keywords Only one keyword per text field only: ferrokinetic, Iron deficiency anemia, treatment


Iron deficiency anemia (IDA) takes the leading place in the Central Asia among all other pathologies. The frequency of IDA in women and children in some regions of Uzbekistan is about 80-90%.
Purposes:
1. To investigate the indexes of ferrokinetic in fertile women suffering from IDA (first degree)
2. Treatment of fertile women suffering from IDA (first degree)
Materials and methods:
25 women with the first degree of IDA have been examined. Diagnosis of IDA verified according to the generally accepted clinic-lab criterions. The calculation of peripheral blood cells has been done on the hematological cell counter. The index of hemoglobin was conducted by colorimetrical ferrocianide method. Serum ferritin and trasferrin were determined by immunnofermentative method.
Results:
The patients were subdivided into 2 groups. 1st group comprised 10 women which received only ferrotherapy. The second group – 15 women, got complex treatment (ferrotherapy plus Succinasol). Patients complained about general weakness, quick fatigability, giddiness, palpitation, paleness and dryness of skin, weak nails, hyperkeratosis, intensive hair falling and growing them dim, stomatitis, pica chloratica etc. Average indexes of hemograms: hemoglobin – 100,8±4,3; erythrocytes: 3,6±0,5*1012; color index: 0,7±0,1; average maintenance of hemoglobin in erythrocyte was 21.5mkg, of retyculocytes: 4,1±1,8‰. Considerable changes of thrombopoiesis and leucopoiesis have not been detected. The maintenance of serum iron is 7,1±1,5 mmoles/ liter. Content of serum transferrin was increased and coefficient of transferrin saturation decreased to 5,1±1,05%. Low level of ferritin testifies about emaciation of depot storage of iron (16,1±2,3mkg per liter). Thus, in fertile women with IDA the serious dysfunctions of ferrokinetic have been established that expressed in decreasing of iron storage of an organism. In complex treatment of IDA in the 2nd group of patients we used ferriferous medicines as well as a new blood substitute hemocorrector Succinasol that was invented in the Institute of Hematoly and Blood Transfusion of Uzbekistan. The treatment course comprised 15 days, number of transfusions of Succinasol per course – 3 times (1 injection per 5 days). A single dose of Succinasol - 200ml Intravenously. The patients noticed improvement of their general physic condition; we detected an instant and stabile normalization of peripheral blood and ferrokinetic indexes. Treatment the 2nd group of patients was not effective for that period (15 days), normalization of the indexes hasn’t been determined. Succinasol has a component of Crebs cycle – the amber acid, which has an unique ability to join in process of oxidation in conditions of hypoxia. As a result in a unit of time amber acid assists to synthesize more adenosine triphosphoric acid than during oxidation of other substrates. This priority makes Succinasol the most effective remedy in complex treatment of IDA. Learning the long term results (3 month) showed stability of achieved results in the 2nd group of patients.
Summary:
1. In fertile women with IDA revealed profound dysfunctions of metabolism
2. Using the new hemocorrector Succinasol in complex treatment of IDA showed better results than traditional treatment.

http://www.parthen-impact.com/cgi-bin/pco/6_05EHA/public/index.cgi?unit=pub_sessionlist_index&form_id=304&session=2000

eeee buni oqip tushunish uchun universitet bitirish kerak, a unga hozir vaqt yoq...:(

shuladan zora biror bir info chiqarish mumkin bolsa ... Hudo mehribon....

[Hope]

Royal aka,

Assalomu Alaikum!

Man siz etgan vrach'ga dokuemntni yubordim email orqali!


Hope

[Royal]

Royal aka,

Assalomu Alaikum!

Man siz etgan vrach'ga dokuemntni yubordim email orqali!

Hope

Manimcha osha ohirgi tekshirish hulosalariniyam bu yerga qoyilsa yanayam yahshi bolarmidi, chunki forum azolari ham oldin korsatilgan joylarga yuborishardi...hatlariga qoship.

[Royal]

Wey.... shuncha aqillari vij-vij bollalarimiza boru, birortasi: man bir-ikkita murojat hati yozip beriy , osha har hil instetutu , shifohonayu va biror bir yordam qiladigan joylaga demaptiya....shuncha 200-300 varaqlik businiss planla yoziladiyu , lekin 2-3 varaqlik hatti yozishga yordam qolini yozmasayla endi....

[Hope]

Dear all,


I just posted a new EXCERPT that I just received from Malika's doctor: http://forum.arbuz.com/attachment.php?attachmentid=21454&d=1179953940I will post some more documents soon.


Hope

[The Reaper]

are you sure it´s not a lie?? Here n germany we have such adverisements alldays.

Your Highness, please do us a favor and bother your Royal-self by reading this whole thread right from the first page.
And be sure to come back with your conclusion.

Your lack of situational awareness, and plain ignorance shown during your short presence here is quite telling.

TR

[Sirena]

Afsuski habarni tanish bilishlarga tarqatishdan boshqa yordam bera olmayman:(

[The MINUSCULE MAN]

To Genius: Problemi:
1. pri zagruzke sayta, ne znayu pochemu, no otkrivaetsya medlenno (mojet toka segodnya, v proshliy raz problem ne bilo).
2. probelma s Button spread the word. Prishlos' otpravlyat' na e-maili directly, prosto hotel chto-bi u nih proper link bil na website.

[noodles]

1. pri zagruzke sayta, ne znayu pochemu, no otkrivaetsya medlenno (mojet toka segodnya, v proshliy raz problem ne bilo).
Ya daje cherez dial-up normal'no zahoju, nu ya proveryu eshe raz.

2. probelma s Button spread the word. Prishlos' otpravlyat' na e-maili directly, prosto hotel chto-bi u nih proper link bil na website.
A chto za problema s knopkoy?

[sumalak]

Hope,

can you put PayPal donate button in your post?

Thanks

[Hope]

Sumalak,


I added the Website address & Link for making Donation to the main post!

Thank you!

Saida

[Пушкарева]

Saida, I recently got email about the case and forwarded the information to the people I know. Some got back to me thinking it was my case and some wondered if it was not a fraud and how I knew about that.

I tried to convience them that it is real since I've been monitoring the case at the site. I hope you'll be ok if some will call you in US to verify the information. Also, I spreaded the appeal among people in an international organization in Tashkent asking to send it further among staff of their counterparts. Therefore, some people might call yoru family in Tashkent to verify the information as well.

I hope it will help somehow.

[Hope]

~*NeZaBudkA*~,


Thank you so much for doing this! It is so kind of you! Right, I think if they contact me directly they will have less uncertinity as to whether it's a real case. Believe me, since the website was opened there were so many people calling me and expressing their sincere wishes for Malika's cure and offering any help they could. May God hear our and their prayers! Thank you for support and help, and for being with us at this difficult moments for us!


Saida

[Octavarium]

Hey Hope,

Just wanted to let you know that I sent around the message in my office -- you should be hearing from people soon. I am posting this not to show off or because I want you to thank me, but rather to let you know that there are people out there who are not indifferent and to strengthen your hope.

God bless your family.

[Пушкарева]

Update: I saw that you added the scanned docs in teh master post. Don't worry about my below ask. I'll do that for you and will urge the people to contact your parents, if needed.


_______________

Saida, I got the response from the people. But please dont get upset with the message, its natural that people want to verify the information. Once they do (they work at a good place), who knows maybe there will be more people to help.

Sorry, I could not follow the updates on the web. Could you send me a brief message (couple of words what you've respond to the below email) with the links to the web and I will forward the information to the people. Thank you.

my email - nezabudka_123@yahoo.com


Hi, dear Zukhra,

I have distributed the information among our colleagues in the office.
Thank you
for the info but, anyway, could you please verify anyhow that this is
not a spam
as one of colleagues who have experienced the same thing with his
family
relative is saying that the indicated in the letter operation cost in
the Europe
does not look correct at all. That's why I felt that this could be a
spam and
wrote to you immediately to check if the email went out from you.


~*NeZaBudkA*~,


Thank you so much for doing this! It is so kind of you! Right, I think if they contact me directly they will have less uncertinity as to whether it's a real case. Believe me, since the website was opened there were so many people calling me and expressing their sincere wishes for Malika's cure and offering any help they could. May God hear our and their prayers! Thank you for support and help, and for being with us at this difficult moments for us!


Saida

[Hope]

~*NeZaBudkA*~,

I understand it is natural that they are questioning. But here is the supporting response from my Dad to the question (abt. the cost of Bone Marrow Transplantation surgery in Europe):

Qizimsalom!

Germaniyadan kelgan javobda:EUR 178 800 +150 000 deyilgan.

Adang.

I will try to get the written prove abt. the costs of such so surgery in Germany. I will post it here as soon as I get it!

Please let me know if anything else is needed!


Thank you Nezabudka!


-Saida

[Пушкарева]

Saida, sorry for bothering you at this difficult time. I did my best to explain the people. I hope it will help at least somehow.

Your sister is so beautiful. May God grant her recovery.

~*NeZaBudkA*~,

I understand it is natural that they are questioning. But here is the supporting response from my Dad to the question (abt. the cost of Bone Marrow Transplantation surgery in Europe):



I will try to get the written prove abt. the costs of such so surgery in Germany. I will post it here as soon as I get it!

Please let me know if anything else is needed!


Thank you Nezabudka!


-Saida

[Hope]

~*NeZaBudkA*~ ,


I really appreciate your efforts to help us! I wish nobody to live through such times!

She is such an extraordinary beautiful person, very kind and generous. We are 1,5 years apart, but we basically grew up together like twins, went to the kindergarten together...school...even the same grade at the university.

I haven't seen her for 2 years now since I came to school to the US. But, it seems to last forever... I miss her and my family so much, can't wait to go home and give them a big hug...

May mighty God give her recovery!


Saida.

[Maroon]

Here is a link of Josep Carreras foundation

4,000 new cases of leukaemia are diagnosed in Spain each year. The Josй Carreras International Leukaemia Foundation is working towards finding a cure for this illness and improving the quality of life of leukaemia patients. We need your support in the fight against leukaemia.


https://www.fcarreras.org/eng/seccio.php?opcion=5


Hope, you should check them out. It is a very powerful foundation.

[Royal]

Here is a link of Josep Carreras foundation
https://www.fcarreras.org/eng/seccio.php?opcion=5
Hope, you should check them out. It is a very powerful foundation.
Missy

Powerfull organizations needs very powerfull approach..

Letter must be written in very strong way, otherwise they may even take look at..

I mentioned before in my other post that we need here online put it that type a letter so users may downloaded and change some info there and send it to applicable organizations...

That would be help also.

[Maroon]

Missy

Powerfull organizations needs very powerfull approach..

Letter must be written in very strong way, otherwise they may even take look at..

I mentioned before in my other post that we need here online put it that type a letter so users may downloaded and change some info there and send it to applicable organizations...

That would be help also.

No one is denying that.

[UzLand]

Saida,

I saw this article today. Please read. May be you wanna talk to this organization about your sister. They work with hospitals that volunteer to help in certain circumstances and cover surgery costs of up to 50-60 thousand dollars.

Toledo area offers Tajik children a chance to have healthy futures

http://toledoblade.com/apps/pbcs.dll/article?AID=/20070621/NEWS32/706210362

The organization's web-site - http://www.isohimpact.org

[UzLand]

Also, I have a suggestion. If I have your permission, we could make 2-3 minute video footage about your sister and her case and upload on YouTube and another video-sharing web-site I came across today - GodTube.com. The latter is a Christian video-sharing web-site, but today Christian charity organizations have greater potential to help with actual help. On the other side, it would be a nice opportunity for them to demonstrate religious tolerance and diversity through a real action.

I would use music, your sister's pics, medical conclusion, letters of support and textual appeal to individuals and organizations for help.

What do you say?

[Hope]

Mrs.Reaper,

Thank you for the link of Josep Carreras foundation! I am sorry for writing this a little bit late. But I wrote to this organization, and waiting for their anwer. Hopefully they will respond soon!

Saida

[Hope]

Uzland,


I read the article abt. the help that Toledo organization provided to Tadjik kids. It's impressive! I will contact them! Hope this help is not limited to Tadjik kids only.

Video footage would be really helpful! Please let me know what you need for it!

Thank you Uzland!

Saida

[-Benom-]

Assalamu alaikum...

Uzland: Someone from my Brothers was busy last days with organizing this kind of Video Clip and he was planning to put it in youtube...

Hope: Soon (in 1 hour) the link for that clip will be put in youtube. We hope that this will be somehow usefull and helpfull in this case.

PS: Ofcourse we are not Professionals but Uzland do not change your mind in making Clip. Maybe the clip you will make will sound more professional...

PS2: Guys I must post min 25 posts to paste here links...What a strange rules here?!...
Whatever, I will edit this post and put the link in my signature....

kind regards
Benom...

[noodles]

-Benom-,

You can pm us the link, and we'll post that.

ps:
PS2: Guys I must post min 25 posts to paste here links...What a strange rules here?!...

this is to avoid different spam advertisements, sorry.

[-Benom-]

-Benom-,

You can pm us the link, and we'll post that.

ps:

this is to avoid different spam advertisements, sorry.
thanks,
PM is sent.

The Quality of the Video was ok, but

after uploading it in Youtube the quality has lost its originality : (...

PS: If someone needs Original swf,wmv,mpg highquality format of this clip please PM me, I will try to upload them in some Hosting servers...

respectfully,,,

[noodles]

Thanks -Benom-!
Here's the youtube link:

http://youtube.com/watch?v=wUxjIbu81Ms

[noodles]

-Benom-,

Thank you for a great job!

If it's possible, it would be easy to read and understand the texts if you slow down a bit the crossfades between frames... keep up the good work!

[Пушкарева]

Just few suggestions.

The text (in the youtube clip) goes somewhat fast that is a normal reader will nto be able to follow the information. Also, there was a note with important info (contacts or smth), so its font is too little. I think that piece of information should be hgihlighted in large.


Thanks -Benom-!
Here's the youtube link:

http://youtube.com/watch?v=wUxjIbu81Ms

[Unique]

I wanted to say the same as Nezabudka. Some parts of the text are running little bit faster that I can't catch words. Over all, you did a great job!
I'll try to promote this video as well.

[-Benom-]

-Benom-,

Thank you for a great job!

If it's possible, it would be easy to read and understand the texts if you slow down a bit the crossfades between frames... keep up the good work!
Nezabudka:
Unique:

If you watch the original Video you can not find such problems, small fonts are also visible, but when you upload it in youtube the file automatically looses its original quality...
but we will try to remake and improove this clip soon, the highlighed texts will be movin slowly.. (the problem is that the when you have huge information it is usually difficult to shorten, bythe same time to be successfull in giving the message to the watcher)...
Whatever thanks for remarks, we will try our best next time...

hopefully Benom...

[Пушкарева]

And also, just a suggestion, since you'll be editing it. Why dont you use a different text color? There are few places when the background is rather white (light). Therefore the white text on the light background is not as vivid as it would be once you change its color. Maybe yellow with think black border line (or red).

That's so good of you. My respect.


Nezabudka:
Unique:

If you watch the original Video you can not find such problems, small fonts are also visible, but when you upload it in youtube the file automatically looses its original quality...
but we will try to remake and improove this clip soon, the highlighed texts will be movin slowly.. (the problem is that the when you have huge information it is usually difficult to shorten, bythe same time to be successfull in giving the message to the watcher)...
Whatever thanks for remarks, we will try our best next time...

hopefully Benom...

[UzLand]

Benom,

do not use effects on text. Just use dissolve and keep the text a little longer. Effects usually distract.

[Hope]

Benom,

Thanks for doing this youtube video! You guys did great job! It will be so helpful!

Thanks to everyone for suggestions. I also think the words in the video are running a little bit fast, I couldn't catch everything, and at times the letters are not seen because of the same color background. If this could be changed a little bit it would be just great!

Also, I will send you some more pictures of Malika, if that could be included in the video too.

But, THANK YOU guys so much for making this video footage! It is so kind of you!!!


Saida

[Hope]

Guys,


Can anyone, please, help us translate the info @ www.mehr.uz into Uzbek language? We already have Russian, English, German versions there running, but also need Uzbek version! I have been trying to translate myself, but I am not good at translating into Uzbek literary language, so it's not coming out right.

Hope

[Maroon]

It was so nice to see the list of the people who made a donation.

Seriously, even 20 or 30 dollars means a lot.

I am sure most of forum users are able to donate that amount.

Thanks.

[Maroon]

Mrs.Reaper,

Thank you for the link of Josep Carreras foundation! I am sorry for writing this a little bit late. But I wrote to this organization, and waiting for their anwer. Hopefully they will respond soon!

Saida

Please let me know when you get a reply! I am sorry I missed your post, I just noticed. I really hope that they will be able to help.

Josep Carreras one way of getting donations is through jewelery. Chopard has a Josep Carrera collection and part of the money goes to the foundation.

[-Benom-]

Uzland:
Genius:
Hope:

We have replaced the Clip, removed the old one from youtube. In new one you can find more detailed info about the Patient and the texts are more readable. (Remarks of all above Users were taken into account)
I will be putting the link into my signature, and will PM some Moders who can put the direct link here...

hopefully...

[nemets]

Uzland:
Genius:
Hope:

We have replaced the Clip, removed the old one from youtube. In new one you can find more detailed info about the Patient and the texts are more readable. (Remarks of all above Users were taken into account)
I will be putting the link into my signature, and will PM some Moders who can put the direct link here...

hopefully...
here it is:
YouTube - Please HELP 19 year old girl with Blood Cancer!

[UzLand]

Hope,

here is the video. What do you think?

YouTube - About a 20 year-old girl from Uzbekistan who has leukemia

Save a 19 year-old girl from Uzbekistan who has leukemia and needs a surgery

We should send it to as many people as possible.

[Royal]

Hope,

here is the video. What do you think?

http://youtube.com/watch?v=7YHb-lkxyrU

We should send it to as many people as possible.
blin man Chaplin chiqipqosa keray dip turipman bir chetta...

endi muniyam bir niamalaga aylantirvormayla endi...

Undan korasi hech bomaganda USga viza oberishni yolini qilila..u yogini dohtirlani ozi eplavorishadi....

[UzLand]

endi muniyam bir niamalaga aylantirvormayla endi...



кизиксиз-а...пул туплаш учун public awareness деган нарса булиши керакми?

[Hamid]

was looking through donations, how much does the paypal charge?
Does it charge around 6.2 for 100 USD???

hh

[Hope]

Hamid,


No, PayPal charges $3.20 fee for $100.


Hope


was looking through donations, how much does the paypal charge?
Does it charge around 6.2 for 100 USD???

hh

[moroti]

Hope,

One of the oil companies launched a charity clinic in Chilanzar (11 kvartal). That might be a good thread to try - talk to the head of the clinic - he is a very nice guy. I think there is a good chance they might help, if you prove your case well.

good luck with that!

[Hope]

La Vie,

Thank you for Translating the text into Uzbek! I really appreciate it! I will try to find someone to proofread it.

I also noticed that Guest Room in the website (www.mehr.uz) is not working. I emailed Genius asking to check what's wrong.

Thank you again,

Hope

[Hope]

Moroti,


Do you know what's the company called? or their contact address?

I will definately try if you could give me some info abt. them.


Hope


Hope,

One of the oil companies launched a charity clinic in Chilanzar (11 kvartal). That might be a good thread to try - talk to the head of the clinic - he is a very nice guy. I think there is a good chance they might help, if you prove your case well.

good luck with that!

[noodles]

I've turned off the Guestroom section because of dozens of spam and some problems with mail headers (empty field), I'll try to repair that.

[moroti]

Hi Hope,

Apologies for the delay - for some reason, it was not possible to login with proxies. As the site is blocked, there was no way of responding to you earlier.

I don't know the exact address other than it is in Chilanzar 11 kvartal, not far from Farhod bozor. I'm pretty sure, if you ask around there, you'll easily be directed there.

It's ZeroMax, but I don't think the name will help you.

Just go there and talk to them. Tell them the opportunities you have looked up and the support you've got internationally!!! - this is key. Present the case well, and I'm pretty sure they can easily support you all the way through. Their investments in health sector in dozenz of mlns.

If you are not in Tash, get their phone and call the guy (the head of the clinic) personally. Tell him where you calling from, explain him and then ask the parents to follow up.

I hope this is of help and best of the luck,

Moroti,


Do you know what's the company called? or their contact address?

I will definately try if you could give me some info abt. them.


Hope

[The Reaper]

Hi Hope,

Apologies for the delay - for some reason, it was not possible to login with proxies. As the site is blocked, there was no way of responding to you earlier.

I don't know the exact address other than it is in Chilanzar 11 kvartal, not far from Farhod bozor. I'm pretty sure, if you ask around there, you'll easily be directed there.

It's ZeroMax, but I don't think the name will help you.

Just go there and talk to them. Tell them the opportunities you have looked up and the support you've got internationally!!! - this is key. Present the case well, and I'm pretty sure they can easily support you all the way through. Their investments in health sector in dozenz of mlns.

If you are not in Tash, get their phone and call the guy (the head of the clinic) personally. Tell him where you calling from, explain him and then ask the parents to follow up.

I hope this is of help and best of the luck,

It's already a work in progress with Zeromax.
They already visited a clinic affiliated with Zeromax, and gave them the papers from the German clinic.

I spoke with the girl's father couple of days ago, he was expecting their follow-up call. If everything comes out okay, according to the head of the clinic, they will pay the remaining sum required to send her to Germany.

I'll update you guys as soon as I hear from Sobir aka.

TR

[moroti]

Great job TR! Let your good deeds be rewarded well!

[VatanparvaR]

Malikani Qirg'izistonga olib borishdimikin, xabar bormi ?
Ahvoli yahshmi :rolleyes:

[farruh.03]

I spoke with the girl's father couple of days ago, he was expecting their follow-up call. If everything comes out okay, according to the head of the clinic, they will pay the remaining sum required to send her to Germany.

I'll update you guys as soon as I hear from Sobir aka.

TR

nima bo'ldi, The Reaper? nimaga hech qanaqa xabar yo'q? tinchlikmi o'zi?:(

[UzLand]

Here is the latest from Saida, Malika's sister

Malika is doing a little better Thank God! I wasn't able to inform of any news in the forum, because I am in Tashent right now and cannot access forum.arbuz.com.

I am so glad I can be together with my family at this difficult time. May Allah hear our prayers ... and help us bring her into normal life!

We have talked to ZEROMAX it Tashkent. They promised to help us. They said that they contacted a German Clinic and waiting for that side's response regarding the possibility of Malika's medical treatment over there. So right now we are waiting to hear good news... We are really hoping this option works out! May God bless her!

[Fifi]

. They said that they contacted a German Clinic and waiting for that side's response regarding May God bless her!


shu to'g'risida keyinchalik ma'lumot bo'lsa beringlar, ya'ni qaysi klinika va qachon?

[noodles]

Bitta savol - xronicheskiy leykozmasmi?

[noodles]

www.mehr.uz saytidan hozirgi kungacha 81,38US$ tushdi... oxirgi paytla umuman odam kirmi qo'ydi... qani bitta-bitta kirib reklamalani bosvorila :)

[noodles]

klassno... uje 93,13US$ :)
davayte po aktivnee ;)

[Prudence]

Hi ppl, I am sorry, I couldn't make the translation earlier, but it is always better late than never, so here are my 50 cents. I have checked the site and translated some parts, which are not translated yet, so Genius, could you please be so kind to change the text on the following:

1. Main page (some columns on the right side of the window):

Пожертвовать
Our work is only possible through the donations made by people like you. Please, donate using the link below:

Сделать пожертвование

Наша работа возможна только посредством пожертвований, сделанных такими же людьми как и Вы. Пожалуйста, сделайте пожертвование, воспользовавшись ссылкой, данной ниже.

2. Spread the world...
Tell a friend...
Guest room
Guest room

Распространить информацию...

Рассказать другу...

Гостевая комната...

Гостевая комната...

3. Tell a friend window

Spread the word about this website by telling your friend(s) about it!
Ваше имя: *

Your name as it will appear in the sent e-mail.
Ваш адрес e-mail: *

Your e-mail address as it will appear in the sent e-mail.
Your friend's e-mail address: *

Seperate multiple e-mail addresses with commas.
Your Personal message:
I found this great web site, which you should really check out!
Add your personal message to the e-mail.
Send yourself a copy.
Message to be sent:
You are invited to check out Mehr at http://www.mehr.uz

Распространите информацию об этом сайте, рассказав о нем другу (друзьям):

Ваше имя
Ваше имя, которое будет указано в посылаемом письме.

Адрес Вашей электронной почты
Адрес Вашей электронной почты, который будет указан в посылаемом письме.

В случае наличия двух и/или более адресов получателей, отделяйте их запятыми.

Ваше личное сообщение:

Я нашел (нашла) этот замечательный сайт, который тебе стоит посетить.

Добавьте свое личное сообщение к данному электронному письму.

Послать себе копию.

Сообщение должно быть послано по следующему (следующим) адресу (адресам):

Вас пригласили посетить следующий веб-сайт http://www.mehr.uz

[Prudence]

4. Contacts

Контактная информация

Если Вы желаете получить подтверждение указанной на сайте информации, Вы можете сделать это, связавшись с семьей Саиды Тулягановой по телефону, электронной почте или посредством личной встречи.

Номер телефона в Убекистане: +998 97 246 3848
Номер телефона Саиды Тулягановой в США: +1 571 236 9178
Адрес электронной почты: saida_uzb@yahoo.com


По техническим вопросам просьба обращаться по следующему адресу:

100083, Ташкент,
улица Усмана Носира, 20/7
Телефон: (+998 71) 153-16-05
Мобильный телефон: (+998 97) 337-88-80
Адрес электронной почты: info@oddiy.uz
ООО "Oddiy Design Studio"

[Prudence]

5. Donate

Сделать пожертвование


Сделать пожертвование через PayPal


Ниже предоставленна информация по банковскому счету для перечисления в долларах США:

Имя бенефициария: Туляганов Сабирджан Туляганович
Номер банковского счета бенефициария: 20206840699009169001
Банк бенефициария: АО "TURONBANK"
Республика Узбекистан, 700011, Ташкент,
улица Абая, 4A МФО 00446
SWIFT: TUROUZ22

Банк-корреспондент: АО "Внешторгбанк", Россия
Номер банковского счета: 30112840255550000061
SWIFT: VTBR RU MM


Информация по банковскому счету для перечисления в сумах - национальной валюте Республики Узбекистан:

Номер банковского счета: 29801000400000446108
МФО: 00446
Банк: АКБ "Турон"

[Prudence]

Genius, could you please be so kind to replace "Пожертвовать" with "Сделать пожертвование", as even if there is a tiny difference between these expressions but the second one suits better. Thank you in advance.

P.S. Zadanie vipolnila, po reklamnim knopochkam proshlas. Good luck to everybody.

[Prudence]

6. Отчет о сделанных пожертвованиях.

Сотни дюдей, групп людей и организций с разный точек мира уже сдлали пожерьвования. Кроме того, мама одного из пользователей форума стала донором для переливания крови Малике. Самое малое, что могут предложить остальные пользователи форума и другие люди, знающие о данном случае, это моральня поддержка, а также помощь в решении организационных вопросов.


Отчет о сделанных пожертвованиях по состоянию на 6/8/2007

Дата Имя Сумма



*** Примечание: Небольшой процент был наложен на большинство платежей, пришедших через PayPal.

P.S. I skipped the translation of names, but if you think that it is necessary, I can do that too.

[Пушкарева]

People, the paypal thing has a right hand log in link. Do I have to register to use it?

Any updates about Malika?

[The Reaper]

I just had a meeting with UzLand, and we came up with another idea to attract more traffic to Malika's website.

1) English language video about Malika and her condition will be created.
2) Then it will be posted on YouTube, or any other video hosting site.
3) Embed the video to the website's main page.
4) Use Digg, StumbleUpon, and Reddit to bump up the website on their listings. Those who do not already have accounts there, could easily sign up to help along. With the number of users we have here, we could easily put it up on their lists.

The resulting incoming traffic that we attract could help raise more money for our cause, and raise people's awareness.

Genius (Noodles (?)): Is it doable? Anything we need to know? In case the traffic gets big, can the server handle it? Even if donations don't meet our expectations, can we at least embed Google Ads to the website, in order to use the resulting traffic to attract Ad money?

What do you guys think?

Otherwise, we don't have any updates yet.

TR

[Asadbek]

Video haqida yaxshi fikr qilibsizlar, The Reaper.

Voice of Amerikaning websahifasida Malika haqida video yo'qmidi?
... more traffic to Malika's website.

Men hozir Malikaning websahifasiga o'z websahifamda Link (http://www.htwm.de/truziboy/uzbek/uzbekistan.htm) qoldirdim.

[Asadbek]

Voice of Amerikaning websahifasida Malika haqida video yo'qmidi?

Men UzLand tayyorlagan mana bu Clipni aytgan ekanman...

[noodles]

First news is bad news:
Мы узнали, что на объявлениях, размещенных на Вашем сайте, выполняются
недействительные клики или показы, поэтому Ваш аккаунт Google AdSense
был заблокирован. Эти действия были предприняты для защиты интересов
рекламодателей AdWords.

So, we are done with Google AdSense. But we can put Yahoo or Yandex ads and they pay almost same as Google ;)


Secondly, now I have some time so that I can update the website. Many thanks to you, I got all translations and corrections so I'll try to update them asap.

The Reaper, yes we can put different traffik-generator buttons, e.g.: stumble upon, reddit... etc., it's not a problem. Don't worry, I hope we won't have any problems with the traffic generated, we have much bandwidth for that site but even if there would happen anything that hosting server won't be able to handle with the requests I hope it could be recovered asap.

[Royal]

Hope ozi keldimi ?

[Queen]

Hope ozi keldimi ?

yo'q ular 16chi Septemberda keladilar. O'zbekistondan forumga kirish imkoniyatlari bo'lmadi.

[noodles]

Men UzLand tayyorlagan mana bu Clipni aytgan ekanman...
Menda faqat "loading" yozuvi chiqyapti, video esa "play" bo'lmayapti.

[noodles]

Here (http://www.mehr.uz/ru/node/8) I've embedded the video for testing - if you have any ideas, drop a line.

[lost]

Nima yangilik bor Malikadan, xabardorlar bormi :(

Odamlaga hayronsan, yiliga qancha odam hajga boradi 5-6 ming $ to'lab,
20 ta odam bormay shu qizga berganlarida, tuzalib ketardi allaqachon :(

qanchadan qancha haromxorlik, foxishabozlik, aroqxo'rlik, qimorbozliklarga ketgan xarajatlarni eslamay, aynan hajga borayatganlarni misol qilib keltirganiz g'alati bo'libti.
: )

gapizni noto'g'ri deganim yo'q, ob'ektivlik yo'qolmasin deymanda faqat...


Insh. qo'ldan kelganicha yordam beramiz...

[VatanparvaR]

qanchadan qancha haromxorlik, foxishabozlik, aroqxo'rlik, qimorbozliklarga ketgan xarajatlarni eslamay, aynan hajga borayatganlarni misol qilib keltirganiz g'alati bo'libti.
: )

gapizni noto'g'ri deganim yo'q, ob'ektivlik yo'qolmasin deymanda faqat...

Insh. qo'ldan kelganicha yordam beramiz...


lost, siz aytgan qanchadan qancha haromxorlik, foxishabozlik, aroqxo'rlik, qimorbozliklarga ketgan xarajatlarni egalarida iymon, etiqod, birovga yahshiliq qilishi hissi bo'lganida ular siz aytgandek haromxorlik, foxishabozlik, aroqxo'rlik, qimorbozlik bilan shug'illlanishmagan bo'lishar edi, teskarisi bo'lganda men albatta ularni eslagan bo'lardim.

Yordam berish extimolligi bo'lgani uchun, hajchilarni aytgandim. Vaqt o'tib ketyapbdi, haj kutib turar, kasal kutmaydi afsus, yoshgina qiz kundan-kunga solib borayapti ahir ko'z oldida :(:(:( :(

[Royal]

.... iymon, etiqod, birovga yahshiliq qilishi hissi bo'lganida ular siz aytgandek haromxorlik, foxishabozlik, aroqxo'rlik, qimorbozlik bilan shug'illlanishmagan bo'lishar edi, teskarisi bo'lganda....

Bu dunyo jannatday bolardiyam....

[Black]

Bugun Internetni titkilab o'tiruvdim, chechenlarni bitta sayti uchrab qoldi. O'qib, "ha, chechenlarga qoyil qolsa bo'ladi" deb o'yladim.

U yerda biznikiga o'hshash situatsiya ekan. Hamma postlarni o'qib chiqmadim, lekin bitta post e'tiborimni tortdi.

19) adlan555 (16 августа 2007 20:35)


САЛАМ АЛЛЕЙКУМ Я ИЗ ФРАНЦИИ ЛУДЩЕ БЫЛО БЫ АДАМУ ПЕРЕЕХАТ В ФРАНЦИЮ ТАК КАК ЗДЕСЬ ЕМУ НЕБЫЛО БЫ ПРОБЛЕМ С ЛЕЧЕНИЕМ ТАКИЕ ОПИРАЦИЕ И ЛЕЧЕНИЕ В ФРАНЦИИ ДЕЛАЮТ БЕЗПЛАТНО ЕСТЬ МНОГО ПРИМЕРОВ ДА И ЧЕЧЕНОВ ЗДЕСЬ МНОГО ЧТОБ ПОМОЧ. ДАЛ МАРШАЛ ДОЙЛ ХУН АДАМ.

Mana shu sayt. http://www.teptar.com/2007/08/14/adam.html
Bu bola ham миелобластный лейкоз ekan.
Kimni vaqti bemalolroq bo'lsa, hamma postlarni o'qib chiqib, foydali malumotlar bo'lsa bilib olsa bo'ladi. U yerda yozilishicha davolanishga 60 000 USD ketarkan. Katta summayu, lekin Novosibirskdagi 80 000 ga qaraganda arzonroq.
Alloh barchalariga shifo bersin.

[benq35]

НОРЕ - а есть ли какойто результат?
Вы сколько уже собрали средств.
Точнее сколько еще надо собрать?

[Royal]

Hope keldimi ozi Toshkentdan yoki yarim yolda uzatvorishdimi nima bolo ?

[Hope]

Hello everyone,

I am very sorry I couldn't update the forum of any news for a long while. I was visiting my sister Malika, my family in Uzb. and recenlty came back to US.
It was painful but at the same time alleviating to see her with my own eyes.
Her health condition seems ok, but only due to medical treatment being taken, which lasts for only a month. She has to be continously getting "Chemotherapy" treatment otherwise she becomes very weak & sometimes can't walk, or eat normally.

We still haven't heard from ZEROMAX yet. They told us to wait until September til' they fix their problems. But so far no sign yet. We're still hoping...

Some more money was transferred to Malika's account via PayPal. But it is still not enough. Thanks to all those kind people who sent money for her Malika's surgery!
I will post an updated amount of funds in a while.

May this holy month of Ramazon bring happiness and joy to your houses and make you closer to God!



Hope

[Fifi]

We still haven't heard from ZEROMAX yet. They told us to wait until September til' they fix their problems. But so far no sign yet. We're still hoping...

Some more money was transferred to Malika's account via PayPal. But it is still not enough.

Hope


Iltimos, hamma forumdoshlar, chet davlatdan homiy topishga kirishinglar.

[Queen]

www.mehr.uz when is it gonna begin working?

[UzLand]

A picture taken while I was at Malika's house...

Malika is on the left; her sister (Hope) is in the middle.

[Пушкарева]

http://www.mehr.uz/index.htm

Many thanks to Noodles for his labor.

www.mehr.uz when is it gonna begin working?

[noodles]

www.mehr.uz when is it gonna begin working?

There's some problem with .htaccess on the server so mehr.uz is not working properly, that's why try to type this URL for now: www.mehr.uz/index.htm

Don't bookmark this link though... becuase I'll repair the URL path and will let you know.

[noodles]

The URL path is repaired, it should work now, try: www.mehr.uz

[kipchak]

Просмотри эти линки, стоит того!

альтернативная медицина по раку. - http://cancerguide.org/coley.html

1). Токсин Коули: http://en.wikipedia.org/wiki/Coley's_Toxins был открыт Коули в конце 19 века и успешно применялся в течение всего 20-ого века. Коли заметил, случаи выздоровления рака у больных рожистым воспалением. Он грубо говоря, заражал "рожей" больных раком. Они температурили до 42, но выздоравливали. Уже 100 лет этому методу. И что вы о нём знаете? - Ничего. Вот даже описано, как этот токсин Коули сделать: http://www.second-opinions.co.uk/coleys_instructions.html

2). Лаэтрил ---http://www.healthfreedom.info/world_without_cancer.htm

3). Сыворотка Буртона, - направленная не на уничтожение, а на создание всплеска собственного иммунитета. http://findarticles.com/p/articles/mi_m0ISW/is_2002_Nov/ai_93736427 Буртон - это учёный имунолог. Ещё 40 лет назад он наладил технологию производств специальной сывортки, то есть специально извлечённую часть крови, которая при введении в кровь больного давала хороший эффект. Результат? Буртона выгнали с работы и он долго лечил раковых больных на Багамских островах, поскольку в США его разыскивало ФБР. Считается уголовным преступлением даже ввозить Сывортку Буртона в США! Будете отвечать как за ввоз наркотика

4) http://www.cancersalves.com/botanical_approaches/historic_practitioners/Hoxsey_treatment.html.

5) http://www.cancure.org/hoxsey_clinic.htm - а вот и клиника, намного дешевле и действеннее по моему.

Опасайся подделок!!!

действующее растительное вещество должно быть в неденатурированной (сырой) форме, так называемой "Ех темпоре", только что приготовленной способом, не денатурирующим продукт.То есть, ни одна лечебная трава не поможет вам ни в какой известной магазинной препаратной форме: таблеток ли, капсул, капель, настоек и т.п. Всё что с полок магазинов и аптек, продаётся в денатурированной форме, предназначенной для хранения, но не для ИЗлечения; в форме, в которой действующее начало дезактивировано. Принимать это бесполезно. Подобное "лечение" - дескредитация натурального лечения.


Удачи, и не теряй надежды.

[Fifi]

Просмотри эти линки, стоит того!

альтернативная медицина по раку. - http://cancerguide.org/coley.html

1). Токсин Коули: http://en.wikipedia.org/wiki/Coley's_Toxins был открыт Коули в конце 19 века и успешно применялся в течение всего 20-ого века. Коли заметил, случаи выздоровления рака у больных рожистым воспалением. Он грубо говоря, заражал "рожей" больных раком. Они температурили до 42, но выздоравливали. Уже 100 лет этому методу. И что вы о нём знаете? - Ничего. Вот даже описано, как этот токсин Коули сделать: http://www.second-opinions.co.uk/coleys_instructions.html

2). Лаэтрил ---http://www.healthfreedom.info/world_without_cancer.htm

3). Сыворотка Буртона, - направленная не на уничтожение, а на создание всплеска собственного иммунитета. http://findarticles.com/p/articles/mi_m0ISW/is_2002_Nov/ai_93736427 Буртон - это учёный имунолог. Ещё 40 лет назад он наладил технологию производств специальной сывортки, то есть специально извлечённую часть крови, которая при введении в кровь больного давала хороший эффект. Результат? Буртона выгнали с работы и он долго лечил раковых больных на Багамских островах, поскольку в США его разыскивало ФБР. Считается уголовным преступлением даже ввозить Сывортку Буртона в США! Будете отвечать как за ввоз наркотика

4) http://www.cancersalves.com/botanical_approaches/historic_practitioners/Hoxsey_treatment.html.

5) http://www.cancure.org/hoxsey_clinic.htm - а вот и клиника, намного дешевле и действеннее по моему.

Опасайся подделок!!!

действующее растительное вещество должно быть в неденатурированной (сырой) форме, так называемой "Ех темпоре", только что приготовленной способом, не денатурирующим продукт.То есть, ни одна лечебная трава не поможет вам ни в какой известной магазинной препаратной форме: таблеток ли, капсул, капель, настоек и т.п. Всё что с полок магазинов и аптек, продаётся в денатурированной форме, предназначенной для хранения, но не для ИЗлечения; в форме, в которой действующее начало дезактивировано. Принимать это бесполезно. Подобное "лечение" - дескредитация натурального лечения.


Удачи, и не теряй надежды.

Edinstvenni'y vi'xod- nujno srochno obnovit' krov'.
Si'vorotka snijaet saxar v krovi, ochish'aet pechen' i zaodno lechit podjeludochnuyu jelezu.

Chto bi' lechit' rak, osobenno zlokachestvennogo xaraktera, nujno unichtojit' razmnojenie rakovi'x kletok putem povi'sheniya temperaturi' organizma, a dlya etogo nujno sidet' na diete i upotreblyat' tol'ko myaso zmei, tak kak eto myaso obespechit imenno povi'shennuyu temperaturu. Takim obrazom mojno vi'lechit' etu bolezn'.

Olloh O'zi bandam desin!

[UzLand]

Мана бу ерда Малика хакида узбек тилида видеолавха. Якинда инглиз тилидагиси хам чикади.

YouTube - A story of an Uzbek girl fighting blood cancer

илтимос, узбек тилини биладиган танишларингизга жунатинг...

Noodles, please place the youtube code in the mehr.uz web-section about Malika

[Queen]

Мана бу ерда Малика хакида узбек тилида видеолавха. Якинда инглиз тилидагиси хам чикади.

http://www.youtube.com/watch?v=fm71ZldHbeU

илтимос, узбек тилини биладиган танишларингизга жунатинг...

Noodles, please place the youtube code in the mehr.uz web-section about Malika

Rahmat katta rahmat qilgan ishizga.

[uzbekcfa2]

juda savobli ish qilyapsiz, uzland.;)

lekin opa-singil ikkalovi ham juda chiroyli qizlar ekan.

Millioner buganimda hamma harajatini bir uzim kutarar edim.:(

Мана бу ерда Малика хакида узбек тилида видеолавха. Якинда инглиз тилидагиси хам чикади.

http://www.youtube.com/watch?v=fm71ZldHbeU

илтимос, узбек тилини биладиган танишларингизга жунатинг...

Noodles, please place the youtube code in the mehr.uz web-section about Malika

[noodles]

UzLand,
Thank you very much for the video. I've placed it (http://www.mehr.uz/blood_cancer.htm) already.

[Пушкарева]

If English subtitles are inserted, the video might make more good.


UzLand,
Thank you very much for the video. I've placed it (http://www.mehr.uz/blood_cancer.htm) already.

[noodles]

If English subtitles are inserted, the video might make more good.

Agree with you. And if possible, please somebody help to translate the text on the main page(only) of the website (http://www.mehr.uz) into russian/german/uzbek etc.

[UzLand]

UzLand,
Thank you very much for the video. I've placed it (http://www.mehr.uz/blood_cancer.htm) already.

I am working on an English version separately with an English voice-over...

Mr.Reaper told me something about the possibility of moving the video up through the YouTube ladder. How do you do that? He said something like people giving their votes to it and bringing it up.

[UzLand]

juda savobli ish qilyapsiz, uzland.;)

lekin opa-singil ikkalovi ham juda chiroyli qizlar ekan.

Millioner buganimda hamma harajatini bir uzim kutarar edim.:(

миллионер булганимда демасдан, миллионер булишнинг йулларини изланг:)

[UzLand]

The English version

YouTube - A story of an Uzbek girl fighting blood cancer - in English

Please circulate among your friends.

[UzLand]

Noodles, could you please replace the Uzbek version of the video on mehr.uz with the English version?

Thanks.

Also Mr. Reaper, you said something about advancing youtube videos through some technique. What was it?

Also, please update her age from 19 to 20 on the web-site...

[Пушкарева]

A friend asked to post this:

Since you guys moderate this web site, please update Malika's age asap - she's 20 years old already, and the information about a 19 years old girl keeps disseminating for more than 1 year, as I have noticed.

And please find the link to the latest version of Malika and her family's interview in English - hope it will be useful. I am currently trying to raise some funds for her here too but the inconsistency of information with regards to her age on video and the web does not help, let's say so.

http://www.youtube.com/watch?v=0TLZUtfT2-8

[UzLand]

Since you guys moderate this web site, please update Malika's age asap - she's 20 years old already, and the information about a 19 years old girl keeps disseminating for more than 1 year, as I have noticed.

And please find the link to the latest version of Malika and her family's interview in English - hope it will be useful. I am currently trying to raise some funds for her here too but the inconsistency of information with regards to her age on video and the web does not help, let's say so.

http://www.youtube.com/watch?v=0TLZUtfT2-8

Do not worry, Vika. I doubt people pay attention to such small technical details. If they want to help, they will help...

[Пушкарева]

I was asked to post this.


People DO pay attention to such kind of details. At least, I definitely would. If not changed, it looks like the campaign on the web does not care about the fact that the girl is growing. It shows that it all started when the girl was 19, now one year has already passed and the amount of money gathered for her is still insignificant and far not enough for the operation. It does not inspire people to give away their money.

So, if you want to consciously keep this technical mistake, please do but be aware that it does not improve the quality of campaign but on the contrary makes it look less reliable and less efficient. And don't forget that you want to attract people's attention and money all over the world to it.

Much more people would be willing to give their money, believing that it would work efficiently. It is not only the question of mercy. It's the question of human way of thinking. Nobody wants to waste their money, so, people won't be willing to donate them to an unefficient campaign which is not able to win. Even if we talk about the matter of life and death. And I personally wouldn't like your campaign to look unefficient.

I know Saida Tulaganova and can send her the copy of this message - what will she think about it? I'm from Uzbekistan myself and have already made the first fundraising for Malika among my own friends. We attracted around 300 dollars, it was the beginning. Now I want to do the second fundraising and know for sure that it would look much more presentable and reliable if the information on the web corresponded to the current information

[Пушкарева]

Noodles, could you please correct the figure on the web? I agree, we should be careful to details and look professional.

The above my friend is very passionate about helping Malika and applies much efforts in raising funds.

Thank you.

[noodles]

Malika's age and youtube link updated. I'll add the German translation of the website as well - Many thanks to GlobalUz for the great job!

[UzLand]

бермуда оролларида хам узбеклар бор экан. отелда ишлашар экан. маликага пул йигишаетган экан. бор булишсин.

[noodles]

The German version (http://www.mehr.uz/de/) is up and running. You can swith to german version from any page by clicking the German Version(http://www.mehr.uz/de/img/de.png) button on the top-right corner. The page about disabled children will be updated as soon as the translation will be ready. We still need to translate the main index page of the site into russian. If you have a time, please, make your contribution.

Now, Hope and other guys, if you know any news concerning Malika's issue, that you think we should write on the website, please let me know and we'll put that. We have to show what is being done so that visitors will see and know that there's an action.

[UzLand]

I have created an online cause for her. Thanks to Globaluz, I learned about this technique and this will be a good tool to colect more donations for Malika. I had to put down an organization as a beneficiary so I put Global Uzbek Council - www.gucweb.org

The money received through GUC will be redirected to Malika.

http://apps.facebook.com/causes/view_cause/36859?recruiter_id=9723542

Please distribute this link to your contacts and friends...

You can also recruit people through Facebook to help with donations.

[corsair]

i ve sent an email to Hope and still waiting for her reply...

[UzLand]

The cause application on Facebook is pretty effective. So far 71 people have signed up as members and potential recruiters. One guy, Timur Khamraev donated 200 dollars. Special thanks to Mrs. Reaper for recruiting people.

http://apps.facebook.com/causes/view_cause/36859

[corsair]

Hope, please check your email.
thank you

[UzLand]

The cause application on Facebook is pretty effective. So far 71 people have signed up as members and potential recruiters. One guy, Timur Khamraev donated 200 dollars. Special thanks to Mrs. Reaper for recruiting people.

http://apps.facebook.com/causes/view_cause/36859

109 people as of today...

[Hope]

Corsair,

I received your message, I will go to pick it up tomorrow! Thank you so much Corsair. I really appreciate it!

[UzLand]

Noodles, do you think you can add a few lines on Malika's page of mehr.uz

Just ask people to send the link to her cause to their contacts

http://apps.facebook.com/causes/view_cause/36859

[corsair]

Corsair,

I received your message, I will go to pick it up tomorrow! Thank you so much Corsair. I really appreciate it!

you are very welcome.

all the best!

[Asadbek]

Assalomu alaykum!

Malikani davolash masalalari nima bo'lyapti? Operaciya o'tkaziladigan joy (shahar, davlat, klinika) aniq bo'lganmi?


Mening bir tanishim bor edi, yaqinda Qondagi rak kasalligi borasida doktorlik ishini himoya qilgan ekan. Adresini topolmay yurgandim. Nihoyat, adresini topib, unga Malika haqida aytib, biror yordam yoki maslahat berishini so'rab, www.mehr.uz sahifasining nemis tilidagisiga Link berib, o'tgan kuni xat yozgandim.
Bugun javob keldi.

Uning aytishicha, AML (Malikaga qo'yilgan diagnoz) ni davolash faqat juda aniq qo'yilgan diagnoz bo'yichagina amalga oshishi kerak ekan va bu odatda oson kechmas ekan. Shu sababli, kasallik holati bo'yicha unga-bunga ayblov qo'yishda ehtiyot bo'lish kerak, dedi. (www.mehr.uz da Malika olayotgan dorilar uning ahvolini yaxshilash o'rniga battar yomonlashtirgan, deyilgan ekanligi uchun shunaqa dedi shekilli...)
Davolash aniq diagnozga qarab, Germaniyada ham ancha qimmatga tushishi mumkinligini aytdi (taxmin keltirmagan lekin...)
U o'zi yordam berolmasligini aytib, mana bu adresni jo'natibdi: http://www.kompetenznetz-leukaemie.de/content/e50/e3921/e3932
Bu sayt faqat nemis tilida, AML bo'yicha tadqiqot olib boradigan institutlar va ishchi guruhlarning ro'yxati bor ekan. Ular Germaniyaning turli burchaklarida.

Men bu guruhlar boshliqlariga bugun xat tayyorlab, yordam so'rab, email jo'natib yuboraman.

[noodles]

UzLand,
Just ask people to send the link to her cause to their contacts

Done! :)

[noodles]

There are several options there for making donation including PayPal, Bank acct. details: http://www.mehr.uz/node/2

Correct the URL please.

[Hope]

Corsair,

I picked up your $300 donation at Western Union yesterday. I can send you recepit. Thanks for contribution to my sister's fund raising. We really appreciate it!

[corsair]

Corsair,

I picked up your $300 donation at Western Union yesterday. I can send you recepit. Thanks for contribution to my sister's fund raising. We really appreciate it!

salomat bo'linglar.

[Hope]

Asadbek,

Malika'ga kerak bolgan operatsiya Hindistonda, Moskva'da, Germaniyada qilinarkan. Faqat hozirgacha yetarli pul yoq.


kasallik holati bo'yicha unga-bunga ayblov qo'yishda ehtiyot bo'lish kerak, dedi. (www.mehr.uz (http://www.mehr.uz/) da Malika olayotgan dorilar uning ahvolini yaxshilash o'rniga battar yomonlashtirgan, deyilgan ekanligi uchun shunaqa dedi shekilli...)


Ota-onam etishlari boyicha, 2006 ylining Fevral oyida kasallik simptomlari paydo bola boshlagan:badanda kop sinyaklar paydo bolavergan, istma chiqavergan, nohushlik... lekin vrachlarga murojat etishganda, hamma analizlar "Yahshi"-bop chiqavergan. Vrachlar oddiy shamollash, qishgi virus deb o'ylab, aslida Leukemia bilan kasallangan odamlaga istemol qilish mumkin bo'magan dorilarni yozib berishgan. Ahvoli esa yomonlashaboravergan. Ohiri Adamla polikninikani glav.vrachiga shikoyat qiganlaridan keyin, rostakasim tekshirishgan analizlarini. Keyin bilsak, Qon Raki ekan.

U o'zi yordam berolmasligini aytib, mana bu adresni jo'natibdi: http://www.kompetenznetz-leukaemie.de/content/e50/e3921/e3932[/INDENT

Linkk'a kirdim, lekin afsus hammasi Nemis tilida yozilgan ekan. English version'ni topomadim
Asadbek, ularga murojat qilayotganiz uchun rahmat! Agar qoshimcha malumotlar kerak bolsa habar bering iltimos.




Assalomu alaykum!

Malikani davolash masalalari nima bo'lyapti? Operaciya o'tkaziladigan joy (shahar, davlat, klinika) aniq bo'lganmi?


Mening bir tanishim bor edi, yaqinda Qondagi rak kasalligi borasida doktorlik ishini himoya qilgan ekan. Adresini topolmay yurgandim. Nihoyat, adresini topib, unga Malika haqida aytib, biror yordam yoki maslahat berishini so'rab, www.mehr.uz (http://www.mehr.uz) sahifasining nemis tilidagisiga Link berib, o'tgan kuni xat yozgandim. Bugun javob keldi.

Uning aytishicha, AML (Malikaga qo'yilgan diagnoz) ni davolash faqat juda aniq qo'yilgan diagnoz bo'yichagina amalga oshishi kerak ekan va bu odatda oson kechmas ekan. Shu sababli, kasallik holati bo'yicha unga-bunga ayblov qo'yishda ehtiyot bo'lish kerak, dedi. (www.mehr.uz (http://www.mehr.uz) da Malika olayotgan dorilar uning ahvolini yaxshilash o'rniga battar yomonlashtirgan, deyilgan ekanligi uchun shunaqa dedi shekilli...)Davolash aniq diagnozga qarab, Germaniyada ham ancha qimmatga tushishi mumkinligini aytdi (taxmin keltirmagan lekin...)U o'zi yordam berolmasligini aytib, mana bu adresni jo'natibdi: http://www.kompetenznetz-leukaemie.de/content/e50/e3921/e3932Bu sayt faqat nemis tilida, AML bo'yicha tadqiqot olib boradigan institutlar va ishchi guruhlarning ro'yxati bor ekan. Ular Germaniyaning turli burchaklarida.

Men bu guruhlar boshliqlariga bugun xat tayyorlab, yordam so'rab, email jo'natib yuboraman.

[W.I.Z.A.R.D]

Corsair,

I picked up your $300 donation at Western Union yesterday. I can send you recepit. Thanks for contribution to my sister's fund raising. We really appreciate it!


Please answer my questions in the personal message.

[Hope]

W.I.Z.A.R.D,


I just did.

[Hope]

UPDATE:


I talked to Malika last weekend. She is feeling OK, as she and my parents say. She is currenlty in the hospital, having chemotherapy.The doctor said her medical test results show that her blood results are higher than normal level, which is not good. He said, too high or too low level means the patient's condition is not very good. She needs a surgery.

The doctor that has been taking care of her is the only experienced doctor in the whole hospital (Hemotology and Blood Transfusion Institute in Tashkent). He got his MS in Hemotology in Russia. Patients do not trust others as much as they trust him. Unfortuantely, he is intending to leave for Russia on November 25th, 2007 to get his Ph.D.
Malika is very sad right now:(

[The Reaper]

Thank you all for your outstanding job!

Can we use Digg to bring Malika's website up on their listings? I don't have a Digg account yet, but I'll create one, and so should you.

If we'll have more than a hundred Digg votes, which is not that much considering the number of users here, we'll dispose her website to much more people around the world.

I'm not quite familiar with Digg and other similar sites, so if there are certain technicalities we should be aware of, please let us know.

EDIT: Done. Someone already created a Digg story about Malika, but the link to her site was broken.
Go HERE (http://digg.com/health/Please_help_to_save_a_girl_with_blood_cancer), register, and vote!

TR

[corsair]

unfortunately its only 3 votes over there...

[noodles]

8 votes already ;)

[UzLand]

The Uzbek party in Dover, NJ on Nov. 24 raised 1,000 dollars for Malika. The head of the Turkistanian-American Association Abdulla Hoja aka will travel to Uzbekistan in 3 weeks to give the money to Malika's family personally.

[NaNiKa]

Hope sistar try to aks help from Oprah 'cuz she help people by donations.....

[UzLand]

The cause application on Facebook is pretty effective. So far 71 people have signed up as members and potential recruiters. One guy, Timur Khamraev donated 200 dollars. Special thanks to Mrs. Reaper for recruiting people.

http://apps.facebook.com/causes/view_cause/36859

166 members by now. 275 dollars raised so far...

[Hope]

The Reaper, thanks for creating Digg account abt. my sister.

I registered, but I am having problem inviting my contacts. For some reason it wouldn't go beyond 2nd step of registration - it freezes. Was anyone able to invite others?

[Patriot.Uz]

I invited 18 friends who r not on digg yet.

[Hope]

A picture of Malika Tulyaganova with her doctor at the Institute of Hemotology and Blood Transfusion where she is getting Chemotherapy. This doctor has been taking care of her. He is a very good doctor. Unfortunately he left for Russia yesterday.

[UzLand]

A picture of Malika Tulyaganova with her doctor at the Institute of Hemotology and Blood Transfusion where she is getting Chemotherapy. This doctor has been taking care of her. He is a very good doctor. Unfortunately he left for Russia yesterday.

too bad:(

facebook has raised 325 dollars so far with 182 people signing up...

http://apps.facebook.com/causes/view_cause/36859

[UzLand]

190 members and $450 have been donated so far...not bad...

http://apps.facebook.com/causes/view_cause/36859

[Nozanim]

Could u plz explain how to make donation? via Facebook?

[UzLand]

Could u plz explain how to make donation? via Facebook?

go to this site

http://apps.facebook.com/causes/view_cause/36859

click on DONATE

[Hope]

I have Updated the Donations Report. I wasn't able to replace the old one in the first (main) post with the new one. B/c this one is long. Can moders or anyone help me to place it to the main post?

I asked to update the Report in the website (www.mehr.uz) too.

[Hope]

$14,639.92 was raised for Malika's surgery as of 12/02/2007. This updated Report has been placed in the Main post (http://forum.arbuz.com/showpost.php?p=529323&postcount=1)

http://img356.imageshack.us/img356/7363/funds1av5.jpg

http://img457.imageshack.us/img457/2795/funds22ym0.jpg

Thanks to everyone who has contributed. Your help is really appreciated!

It has been progressing good! Guys, please help to recruit more people to this.

[noodles]

Now the website (http://www.mehr.uz) is working fully in 3 languages - english, russian and german. I'll update the donations as soon as I get the report in raw format - excel or word format, not image, because it's very hard to recognize the inputs.

If you encounter any mistakes in texts or links, please, let me know. You can PM me or mail to avazbek/at/gmail/dot/com.

I would like to thank everyone who made contributions in translating the content - Prudence, GlobalUz and Nezabudka. Thank you very much for the help.

[UzLand]

Kattalarning oldidan o’tib qo’yay degandim. Ularning maslahati kerak.

Маъмурларнинг олдидан хам утиб куйинг. Тагин варака таркатиш, мазмунидан катъий назар, ноконуний дейишмасин...

[Patriot.Uz]

Маъмурларнинг олдидан хам утиб куйинг. Тагин варака таркатиш, мазмунидан катъий назар, ноконуний дейишмасин...


Unda o'sha ma'murlar varaqa tarqalmasligi uchun muxtojlarga yordam berishsin. Ulardan sado chiqarmikan?! :rolleyes:

Aytgancha, ma'murlar hozir saylov bilan ovora. Shundan foydalanib qolamiz. ;)

[UzLand]

Through facebook $810 have been raised...274 members

http://apps.facebook.com/causes/view_cause/36859

[UzLand]

Hope, have you seen this?

YouTube - Leukemia treatment

[Royal]

Hope, have you seen this?

http://www.youtube.com/watch?v=XRPAeopbJNg

shu dori togrisida dohtirladan yahshilap surishtirila ,
keray bosa oberaman ilojsini qilip...

[Lady_G]

mehr.uz saytidagi Saidaning telefonlari bittasiyam ishlamayabti.

[Royal]

Hope, have you seen this?

http://www.youtube.com/watch?v=XRPAeopbJNg

FDA Approves New SPRYCEL® (Dasatinib) Product Labeling for Patients with Chronic-Phase CML

- Labeling Now Includes Lower Once-Daily Starting Dose and Data from First Randomized Trial of SPRYCEL and Gleevec®*(imatinib mesylate) -

PRINCETON, N.J., Nov. 8 /PRNewswire-FirstCall/ -- Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has approved new labeling for SPRYCEL to include a lower recommended starting dose of 100 mg once daily and safety and efficacy data in a greater number of patients with chronic-phase chronic myeloid leukemia (CML) resistant or intolerant to prior therapy including Gleevec. The product labeling now also includes data from the first randomized trial of SPRYCEL and Gleevec. SPRYCEL is indicated for the treatment of adults with chronic-, accelerated-, or myeloid or lymphoid blast-phase CML with resistance or intolerance to prior therapy including Gleevec. The effectiveness of SPRYCEL is based on hematologic and cytogenetic response rates. There are no controlled trials demonstrating a clinical benefit, such as improvement in disease-related symptoms or increased survival.

"The new, lower once-daily dose reduces the incidence of some side effects while preserving the efficacy of SPRYCEL for patients with chronic-phase CML no longer responding to currently-approved therapies," said Dr. Hagop Kantarjian, M.D., Chairman and Professor, Leukemia Department, MD Anderson Cancer Center. "Importantly, the new clinical data now included in the labeling provides further evidence to support the use of SPRYCEL to treat patients with chronic-phase CML, if their disease is no longer responding to currently available treatment including Gleevec."

The updated labeling was granted priority review and was approved in six months based primarily on two studies that enrolled chronic-phase CML patients with resistance or intolerance to Gleevec. A summary of the changes, which are detailed below, include:

* A lower recommended starting dose of SPRYCEL 100 mg once daily based on a dose-optimization trial - the first Phase 3 trial in this patient population. This once daily dose was associated with a lower frequency of some side effects (severe myelosuppression and fluid retention).
* Cytogenetic responses from the first randomized trial of SPRYCEL, 70 mg twice daily, and Gleevec 800 mg (400 mg twice daily), study -017. For patients receiving SPRYCEL, at 12 weeks 36 percent achieved a major cytogenetic response, the study's primary endpoint (29 percent with Gleevec), and 22 percent achieved a complete cytogenetic response (8 percent with Gleevec). With longer treatment and follow-up, 52 percent achieved a major cytogenetic response (33 percent with Gleevec), and 40 percent of patients achieved a complete cytogenetic response (16 percent with Gleevec).

The updated SPRYCEL labeling encompasses safety data for a total of 2,182 patients.

"We believe that this filing and its subsequent approval further demonstrates our commitment and dedication to patients with this disease," said Claude Nicaise, M.D., Vice President, SPRYCEL Global Development, Bristol-Myers Squibb. "Bristol-Myers Squibb is fully committed to further exploring and understanding the appropriate use of SPRYCEL through a robust clinical development program."

About the Studies

Dose-Optimization (Study -034): The Phase 3, randomized, open-label study was conducted in patients with chronic-phase CML, whose disease was resistant or intolerant to Gleevec, to evaluate the efficacy of SPRYCEL administered once daily compared with twice daily. The primary endpoint was major cytogenetic response in patients with Gleevec-resistant chronic phase CML. A total of 670 patients (498 Gleevec resistant) were randomized to 100 mg once daily, 140 mg once daily, 50 mg twice daily, or 70 mg twice daily. Those patients who received SPRYCEL once daily achieved a comparable (non-inferior) major cytogenetic response to those who received SPRYCEL twice daily. The rate of major cytogenetic response was lower among patients aged 65 years and over. The median duration of treatment was approximately eight months. The study supports the new recommended starting dose, 100 mg once daily, for chronic-phase CML.

Incidence of selected adverse reactions (all grades) in the Phase 3 dose- optimization study in chronic-phase CML patients receiving SPRYCEL 100 mg once daily (n=165) or SPRYCEL 70 mg twice daily (n=167) included diarrhea (23%, 25%); fluid retention events (24%, 32%) such as superficial edema (14%, 16%), pleural effusion (10%, 18%), generalized edema (2%, 1%), congestive heart failure/cardiac dysfunction (0%, 4%), pericardial effusion (1%, 2%), pulmonary edema (0%, 2%), pulmonary hypertension (0%, 1%), and hemorrhage (10%, 14%) including gastrointestinal bleeding (1%, 4%).

In this same study, the frequency of Grade 3/4 neutropenia, thrombocytopenia, and anemia was 34%, 22%, and 10%, respectively, in the SPRYCEL 100 mg once-daily group and 43%, 38%, and 17%, respectively, in the SPRYCEL 70 mg twice-daily group. The frequency of Grade 3/4 hypophosphatemia and hypocalcemia was 8% and 2%, respectively, in the SPRYCEL 100 mg once-daily group, and 7% and 2%, respectively, in the SPRYCEL 70 mg twice-daily group.

The starting dose for adults with accelerated-phase, myeloid or lymphoid blast-phase CML or adults with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) resistant or intolerant to prior therapy remains at 70 mg twice daily.

SPRYCEL and Escalated Doses of Gleevec (Study -017): The Phase 2 randomized, open-label study evaluated SPRYCEL 70 mg twice daily and Gleevec 800 mg (400 mg twice daily) in 150 patients with chronic-phase CML resistant to prior Gleevec doses of 400 or 600 mg. For patients receiving SPRYCEL, at 12 weeks 36 percent achieved a major cytogenetic response, the study's primary endpoint (29 percent with Gleevec), and 22 percent achieved a complete cytogenetic response (8 percent with Gleevec). With longer treatment and follow-up, 52 percent achieved a major cytogenetic response (33 percent with Gleevec), and 40 percent of patients achieved a complete cytogenetic response (16 percent with Gleevec). The rate of major cytogenetic response with SPRYCEL was lower among patients aged 65 years and over.

At the time of analysis, 39 of 49 patients receiving Gleevec had crossed over to SPRYCEL; 15 of 101 patients receiving SPRYCEL had crossed over to Gleevec. Crossover to alternate therapy was permitted in the event of disease progression or intolerable toxicity. Median duration of treatment prior to crossover was 14 months for SPRYCEL and three months for Gleevec.

Incidence of selected adverse reactions (all grades) in the Phase 2 randomized study in patients receiving SPRYCEL 70 mg twice daily or Gleevec 800 mg daily (400 mg twice daily) included diarrhea (37%, 29%); fluid retention events (36%, 43%) such as pleural effusion (23%, 0%), superficial edema (17%, 41%), generalized edema (2%, 4%), congestive heart failure/cardiac dysfunction (2%, 0%), pericardial effusion (1%, 0%), pulmonary edema (3%, 0%), pulmonary hypertension (1%, 0%); nausea (24%, 33%); hemorrhage (18%, 8%) including gastrointestinal bleeding (3%, 0%), and vomiting (10%, 24%).

In this same study, the frequency of Grade 3/4 neutropenia, thrombocytopenia, and anemia was 63%, 56%, and 19%, respectively, in the SPRYCEL group and 39%, 14%, and 8%, respectively, in the Gleevec group. The frequency of Grade 3/4 hypocalcemia was 4% in the SPRYCEL group and 0% in the Gleevec group.

Patients enrolled in this study received SPRYCEL 70 mg twice daily as described earlier. Per the new labeling, the recommended starting dose for these patients with chronic-phase CML is now 100 mg once daily.
...............

[Royal]

Cytogenetic and Hematologic Responses

Major cytogenetic response is defined as complete (0 percent of Philadelphia chromosome-positive [Ph+] cells in the bone marrow) plus partial (less than or equal to 35 percent of Ph+ cells in the bone marrow) cytogenetic responses. Complete hematologic response is a measure of how effective a treatment is in returning blood counts to normal and occurs when blood counts appear normal and patients have no signs or symptoms of disease.

About SPRYCEL

On June 28, 2006, the U.S. Food and Drug Administration (FDA) granted accelerated approval of SPRYCEL (pronounced 'spris-el), an oral inhibitor of multiple tyrosine kinases, for the treatment of adults in all three phases of CML (chronic-, accelerated-, or myeloid or lymphoid blast-phase) with resistance or intolerance to prior therapy including Gleevec. The effectiveness of SPRYCEL is based on hematologic and cytogenetic response rates. There are no controlled trials demonstrating a clinical benefit, such as improvement in disease-related symptoms or increased survival. The FDA also granted full approval of SPRYCEL for the treatment of adults with Ph+ ALL with resistance or intolerance to prior therapy.

Resistance to Gleevec is often due to mutations of BCR-ABL, BCR-ABL over- expression, or activation of new pathways. SPRYCEL is the first approved oral multiple tyrosine kinase inhibitor that, at nanomolar concentrations, inhibits BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRЯ kinases. SPRYCEL is designed to inhibit the overproduction of leukemia cells in the bone marrow of patients with CML and Ph+ ALL and allows normal red cell, white cell, and blood platelet production to resume.

IMPORTANT SAFETY INFORMATION

Myelosuppression:

Treatment with SPRYCEL® (dasatinib) is associated with severe CTC Grade 3/4 thrombocytopenia, neutropenia, and anemia. Their occurrence is more frequent in advanced phase CML or Ph+ ALL than in chronic-phase CML. Myelosuppression was reported in patients with normal baseline laboratory values, as well as in patients with pre-existing laboratory abnormalities. Complete blood counts (CBCs) should be performed weekly for the first 2 months and then monthly thereafter, or as clinically indicated. In clinical studies, myelosuppression was managed by dose interruption, dose reduction, or discontinuation of study therapy. Hematopoietic growth factor has been used in patients with persistent myelosuppression.

Bleeding Events:

Dasatinib caused platelet dysfunction in vitro and thrombocytopenia in humans. Severe CNS hemorrhage, including fatalities, occurred in <1% of patients. Severe GI hemorrhage occurred in 4% of patients and generally required treatment interruptions and transfusions. Other cases of severe hemorrhage occurred in 2% of patients. Most bleeding events were associated with severe thrombocytopenia. Caution is advised in patients required to take medications that inhibit platelet function or anticoagulants.

Fluid Retention:

Fluid retention was severe in 8% of patients, including pleural and pericardial effusions reported in 5% and 1%, respectively. Severe ascites and generalized edema were reported in <1% of patients. Severe pulmonary edema was reported in 1% of patients. Patients who develop symptoms suggestive of pleural effusion (dyspnea or dry cough) should be evaluated by chest X-ray. Severe pleural effusion may require oxygen therapy and thoracentesis. Fluid retention was typically managed by supportive care measures that included diuretics or short courses of steroids. Patients over the age of 65 years are more likely to experience fluid retention events, and should be monitored closely.

QT Prolongation:

In vitro data suggest that dasatinib has the potential to prolong cardiac ventricular repolarization (QT interval). Nine patients had QTc prolongation as an adverse event. Three patients (<1%) experienced a QTcF >500 msec. SPRYCEL should be administered with caution to patients who have or may develop prolongation of QTc, including patients with hypokalemia, hypomagnesemia, or congenital long QT syndrome and patients taking anti- arrhythmic drugs, other medicinal products that lead to QT prolongation, or cumulative high-dose anthracycline therapy. Hypokalemia or hypomagnesemia should be corrected prior to SPRYCEL administration.

Drug Interactions:

Dasatinib is a CYP3A4 substrate. Drugs that may increase dasatinib concentrations are: Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, atazanavir, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, voriconazole). Concomitant use of dasatinib and drugs that inhibit CYP3A4 should be avoided. If systemic administration of a potent CYP3A4 inhibitor cannot be avoided, close monitoring for toxicity and a SPRYCEL dose reduction or temporary discontinuation should be considered. Grapefruit juice may also increase plasma concentrations of dasatinib and should be avoided. Drugs that may decrease dasatinib concentrations are: Strong CYP3A4 inducers (e.g., dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, phenobarbital). Alternative agents with less enzyme induction potential should be used or a dose increase of SPRYCEL should be considered. St John's Wort may decrease dasatinib plasma concentrations unpredictably and should be avoided.

Dasatinib is a time-dependent inhibitor of CYP3A4. Drugs that may have their plasma concentration altered by dasatinib are: CYP3A4 substrates such as simvastatin. Therefore, CYP3A4 substrates with a narrow therapeutic index (e.g., alfentanil, astemizole, terfenadine, cisapride, cyclosporine, fentanyl, pimozide, quinidine, sirolimus, tacrolimus, or ergot alkaloids [ergotamine, dihydroergotamine]) should be administered with caution in patients receiving SPRYCEL.

Long-term suppression of gastric acid secretion by use of H2 antagonists or proton pump inhibitors (e.g., famotidine and omeprazole) is likely to reduce dasatinib exposure. Therefore, concomitant use of H2 antagonists or proton pump inhibitors with SPRYCEL is not recommended. The use of antacids should be considered. Simultaneous administration of SPRYCEL and antacids should be avoided. If antacid therapy is needed, the antacid dose should be administered at least 2 hours prior to or 2 hours after the dose of SPRYCEL.

Pregnancy:

SPRYCEL may cause fetal harm when administered to a pregnant woman. Women should be advised of the potential hazard to the fetus and to avoid becoming pregnant.

Nursing Mothers:

It is unknown whether SPRYCEL is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue drug.

Adverse Reactions:

The safety data reflect exposure to SPRYCEL in 2,182 patients with leukemia in clinical studies (starting dosage 100 mg once daily, 140 mg once daily, 50 mg twice daily, or 70 mg twice daily). The majority of SPRYCEL- treated patients experienced adverse reactions at some time. Drug was discontinued for adverse reactions in 9% of patients in chronic phase, 10% in accelerated phase, 15% in myeloid blast phase CML, and 8% in lymphoid blast phase CML or Ph+ ALL.

The most frequently reported adverse reactions (reported in greater than or equal to 20% of patients) included fluid retention events (37%), diarrhea (31%), headache (24%), skin rash (22%), nausea (22%), hemorrhage (21%), fatigue (21%), and dyspnea (20%).

The most frequently reported serious adverse reactions included pleural effusion (9%), pyrexia (3%), pneumonia (3%), infection (2%), febrile neutropenia (4%), gastrointestinal bleeding (4%), dyspnea (3%), sepsis (1%), diarrhea (2%), congestive heart failure (2%), and pericardial effusion (1%).

Grade 3/4 elevations of transaminase or bilirubin and Grade 3/4 hypocalcemia and hypophosphatemia were reported in patients with all phases of CML, but were reported with an increased frequency in patients with myeloid or lymphoid blast phase CML and Ph+ ALL. Elevations in transaminase or bilirubin were usually managed with dose reduction or interruption. Patients developing Grade 3/4 hypocalcemia during the course of SPRYCEL therapy often had recovery with oral calcium supplementation.

Full Prescribing Information is available at http://www.sprycel.com/.
http://newsroom.bms.com/index.php?s=press_releases&item=315

korilachi balkim yordam qip qolar

[Royal]

SPRYCEL 50MG TABLETS


Request a prescription now

Drug Information For: SPRYCEL 50MG TABLETS

Ingredient Name: DASATANIB (da-SA-ti-nib)

Drug Manufacturer: B-M SQUIBB U.S. (PRIMARY CARE)

Common Uses: This medicine is a tyrosine kinase inhibitor used to treat certain patients with certain types of leukemia. It may also be used to treat other conditions as determined by your doctor.

Before Using This Medicine: Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking certain medicines that decrease stomach acid (such as cimetidine, famotidine, or ranitidine), proton pump inhibitors (such as omeprazole, esomeprazole, or lansoprazole), or St. John's wort. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking alfentanil, certain antifungal medicines (such as ketoconazole, itraconazole, or voriconazole), anthracycline, antiplatelet medicines (such as aspirin, cilostazol, or clopidogrel), astemizole, blood thinners (such as warfarin), cisapride, cyclosporine, dexamethasone, ergot alkaloids (such as ergotamine or dihydroergotamine), fentanyl, HIV protease inhibitors (such as ritonavir or saquinavir), macrolide antibiotics (such as clarithromycin or erythromycin), medicines for irregular heartbeat (such as amiodarone or quinidine), nefazodone, certain medicines for tuberculosis (such as rifampicin or rifabutin), certain seizure medicines (such as phenytoin, carbamazepine, or phenobarbital), pimozide, sirolimus, tacrolimus, telithromycin, or terfenadine. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including heart problems or irregular heartbeat (such as congenital long QT syndrome), lactose intolerance, liver problems, low magnesium or potassium blood levels, bleeding problems, blood in the stool or vomit, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use This Medicine: Follow the directions for using this medicine provided by your doctor. An additional patient information leaflet is available with this medicine. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. SWALLOW WHOLE. Do not break, crush, or chew before swallowing. This medicine may be taken on an empty stomach or with food. DO NOT TAKE ANTACIDS within 2 hours before or 2 hours after taking this medicine. STORE THIS MEDICINE at room temperature at 77 degrees F (25 degrees C) in a tightly closed container, away from heat and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Take this medicine regularly to receive the most benefit from it. Taking this medicine at the same time each day will help you to remember. IF YOU MISS A DOSE OF THIS MEDICINE, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.

Cautions: DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed without checking with your doctor. DO NOT CHANGE YOUR DOSE OR STOP USING THIS MEDICINE without first checking with your doctor. Your dose may need to be slowly lowered to avoid side effects. Laboratory and/or medical tests, including complete blood counts, blood electrolytes, and heart function tests may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR OR LABORATORY APPOINTMENTS while you are taking this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. This medicine may cause dizziness. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. THIS MEDICINE MAY REDUCE THE NUMBER OF BLOOD CELLS THAT ARE NEEDED FOR CLOTTING. To prevent bleeding, avoid situations where bruising or injury may occur. THIS MEDICINE MAY LOWER YOUR RESISTANCE TO INFECTION. Prevent infection by avoiding contact with people with colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR MEN: Use a condom each time you have sex with a woman who can become pregnant while you are taking this medicine. FOR WOMEN: THIS MEDICINE HAS BEEN SHOWN TO CAUSE HARM to the human fetus. IF YOU ARE ABLE TO BECOME PREGNANT, use effective birth control while you are taking this medicine. Talk with your doctor or pharmacist about effective methods of birth control. IF YOU PLAN ON BECOMING PREGNANT while you taking this medicine, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.

Possible Side Effects: SIDE EFFECTS that may occur while taking this medicine include diarrhea, dizziness, fatigue, headache, nausea, vomiting, or stomach pain. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience unexplained fever, chills, or sore throat; cough; or a change in the amount of urine produced. CONTACT YOUR DOCTOR IMMEDIATELY if you experience unusual bleeding or bruising (such as nosebleeds, bleeding from the gums, or changes in menstrual flow); chest pain; confusion; fainting; severe or persistent headache; irregular heartbeat; mood or mental changes; one-sided weakness; black, tarry stools; vomit that looks like coffee grounds; shortness of breath; seizures; slurred speech; sudden weight gain; swelling of the ankles, feet, hands, or legs; unusual tiredness or weakness; or vision changes. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Overdose: IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately.

Additional Information: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIMED, be sure to obtain necessary refills before your supply runs out.http://www.walgreens.com/library/finddrug/druginfo1.jsp?particularDrug=Sprycel&id=649791


Uzr tepadigi pullani hisobini qarap bir fikr kep qoldi, shu pullarni paypal yoki western union ga ohshagan kompaniayladan jonatgandan kora , chunki 3-4-5% gacha oz hizmatlari uchun haq olisharkan, $1.00gachan Money Order olip .40centga jonatsa bomiydimi toppa togri
Hope/Saidani adresiga ???

oshayam ancha ekonom bomasdimi ??? agar hamma summani hisoblasa ancha pul bolarkan lekin..ketgan harajat.

[Hope]

Lady_G,

Yo ishlidi telefonlani hammasi. Man prosto ishda edim, I couldn't answer. I'll contact you right now.

-Hope

mehr.uz saytidagi Saidaning telefonlari bittasiyam ishlamayabti.

[Hope]

Hope, have you seen this?

http://www.youtube.com/watch?v=XRPAeopbJNg

I just watched the above video. Never heard about this drug. But they are talking about CML (Chronic Mylogenous Leukemia) and my sister has AML (Acute Mylogenous Leukemia). But, I saw, though, in one part that it might apply to other kinds of Leukemia as well, so let's hope it applies to AML too.
I'll ask her doctor.

[elliptic]

hi, at first i would like to apologize you for my poor english, but the problem i have is more important than disgrace cause at first i don't know english well and the sacond i can't write the message in forum. my tragedy is an illness of my aunt. we are so desperated :( she was very determinated to live but 5 days ago she heart that she is having 10 cm cancer on her liver, after this words the heart she breaked down :( and it's not good for ill person. she had surgery one over one month ago, doctors told her that all is under control but 5 days ago, after making some examinations doctors saw, that she is having this cancer in liver and now no one want to help us. i read in internet many stories of ill people and thank this i saw an article about medicine name SORAFENIB, but one month use this medicine costs 4.000 euro and it's tragedy for my family cause my family isn't rich :( maybe for some people it is not much but for us it's a fortune, cause it's price for use this medicine for only one month :( as u guess i write this message with dictionary but i hope you'll understand my words to you. please help my aunt. i know that some people will not believe in my words, cause in internet many people want to earn easy money but if there were some people which will believe in my words i and they would like to help us please contact me on email: elliptic@interia.pl if someone would like to give some money for treatment my aunt or better way- who could buy this medicament, me and my aunt would be verry happy. thank you for read this message.

[noodles]

elliptic,
In this thread we're discussing different case. I'd recommend you to open a new thread and post your story there, I hope forum users will do their best to help.

[Joe1980]

hi, at first i would like to apologize you for my poor english, but the problem i have is more important than disgrace cause at first i don't know english well and the sacond i can't write the message in forum. my tragedy is an illness of my aunt. we are so desperated :( she was very determinated to live but 5 days ago she heart that she is having 10 cm cancer on her liver, after this words the heart she breaked down :( and it's not good for ill person. she had surgery one over one month ago, doctors told her that all is under control but 5 days ago, after making some examinations doctors saw, that she is having this cancer in liver and now no one want to help us. i read in internet many stories of ill people and thank this i saw an article about medicine name SORAFENIB, but one month use this medicine costs 4.000 euro and it's tragedy for my family cause my family isn't rich :( maybe for some people it is not much but for us it's a fortune, cause it's price for use this medicine for only one month :( as u guess i write this message with dictionary but i hope you'll understand my words to you. please help my aunt. i know that some people will not believe in my words, cause in internet many people want to earn easy money but if there were some people which will believe in my words i and they would like to help us please contact me on email: elliptic@interia.pl if someone would like to give some money for treatment my aunt or better way- who could buy this medicament, me and my aunt would be verry happy. thank you for read this message.


it seems to me a scam. Olloh uzi kechirsin agar adashayotgan bulsam.

[UzLand]

I am happy to let you know that Abdulla Hoja aka, head of Turkistan-America Association based in NJ was in Tashkent and visited Malika's house. He met with her and her parents and handed in 1,000 dollars raised during the Uzbek event in Dover, on November 24, 2007.

[Lady_G]

www.mehr.uz ishlamayabti.

[noodles]

Lady_G,

Raxmat habar berganingiz uchun. Yaqin vaqt ichida buni sababini aniqlashga harakat qilaman.

[UzLand]

Thru Facebook we've recruited 387 members so far and $1,015 have been raised.

http://apps.facebook.com/causes/view_cause/36859?recruiter_id=9723542

[noodles]

OK,

concerning the website - mehr.uz:
firma, gde ya rabotal ran'she, bol'she ne hochet podderjat' domen/hosting za etot sayt. V nachale kogda tut prosili o sayte, nashe nachalstvo soglashalsya, poetomu i ya pisal ob etom... nu esli bi ya znal togda, chto v budushem vse tak slojitsya.. ya bi ni za chto ne pisal bi... koroche mne na samom dele ne lovko... no horosho chto sayt ne udalili, vse fayli u menya... a naschet domena, domen uje kak bi vezde prisvechen, esli pomenyat' domen na drugoy to dumayu budet kak to ne etichno, mogut podumat' chto sayt yavlyalsa ljivem i vse takoe.. poetomu ya poprosil ih chtob oni osvobodili domen esli ne hotyat ego derjat... nadeyus' oni skoro zdelayut eto, i komu nibud' kto nahoditsya v Tashkente nado budet zaregistrirovat' ego na svoe imya. Esli est' jelayushie, kto pomojet s etim... napishite mne v PM. A hosting ya dumayu naydetsya... eto ne problema.

[VatanparvaR]

Malikani ahvoli yahshimi ?
Kimda yangiliklar bo'lsa, xabardor qilib turinglar, iltimos.

[VatanparvaR]

Hech yangilik yo'qmi?
Qirg'izistonga boramiz deyoshgandi, olib bordilarmi Malikani? :rolleyes:

Habar berib turinglar iltimos.

[saturn]

Маликани ахволидан хабардорла борми???

уйларига тел. килишга нокулай бувотти..... :rolleyes:

[Hope]

Vatanparvar/saturn va boshqalar,

Avvalam bor uzr anchadan beri Forumni singlim Malikani ahvolidan habardor qila olmadim! Malika himiyaterapiya moalajasini olishni davom ettirvotti, hali ham Toshkentta. Qirg'izistonga olib-borib keldik, u yerda Qirg'iz-Turk Transplantatsiya Centri ochilgan ekan. Turk mutahassislarni etishlari boyicha operatsiya orqali davolasa bolarkan bu singlimni. Lekin ular ham juda qimmat deyishdi.
Kecha, 20 Mart kuni Malikani tug'ilgan kuni boldi:) U juda ham hursand, bazi forum azolaridan ham Malikani tabriklab juda ko'nglini kotarishdi. Rahmat silarga!

Forumchilar,

Ichilarda AQSH'dagi Gospital/Klinikalar bilan aloqayla bolgan,
yoki horijiy fuqarolarni davolab kelgan Gospitallarni bilseylar, iltimos manga habar berila!

Rahmat,
-Hope

[Royal]

Forumchilar,

Ichilarda AQSH'dagi Gospital/Klinikalar bilan aloqayla bolgan,
yoki horijiy fuqarolarni davolab kelgan Gospitallarni bilseylar, iltimos manga habar berila!

Rahmat,
-Hope

Dohtir bilan gaplashgandizku ? u nima boldi ?

[Abu Hurayra]

Assalamu 'alaikum,

brodarlar bilan birgalashib www.mehr.sofislom.com sahifasini ochayapmiz, qisqa vaqt ichida tayyorlash niyatidamiz. Loyihaning maqsadi butun dunyodagi insonlarni mehr muruvvat ehsonga chorlashga qaratadi.
Loyihaning kundalik mavzusi ho